Drug Class And Mechanism: Metronidazole is an antibiotic effective against
anaerobic bacteria and certain parasites. Anaerobic bacteria are
single–celled, living organisms that thrive in environments in which there
is little oxygen (anaerobic environments) and can cause disease in the
abdomen (bacterial peritonitis), liver (liver abscess), and pelvis
(abscess of the ovaries and the Fallopian tubes). Giardia lamblia and
ameba are intestinal parasites that can cause abdominal pain and diarrhea
in infected individuals. Trichomonas is a vaginal parasite that causes
inflammation of the vagina (vaginitis). Metronidazole selectively blocks
some of the functions within the bacterial cells and the parasites
resulting in their death.
Prescribed For: Metronidazole is used to treat parasitic infections
including Giardia infections of the small intestine, amebic liver abscess
and amebic dysentery (infection of the colon causing bloody diarrhea),
bacterial vaginosis, trichomonas vaginal infections, and carriers of
trichomonas (both sexual partners) who do not have symptoms of infection.
Metronidazole is also used alone or in combination with other antibiotics
in treating abscesses in the liver, pelvis, abdomen and brain caused by
susceptible anaerobic bacteria. Metronidazole is also used in treating
infection of the colon caused by a bacterium called C. difficile. (Many
commonly–used antibiotics can alter the type of bacteria that inhabit the
colon. C. difficile is an anaerobic bacterium that can infect the colon
when the normal types of bacteria in the colon are inhibited by common
antibiotics. This leads to inflammation of the colon (pseudomembranous
colitis) with severe diarrhea and abdominal pain.) Metronidazole also is
used in combination with other drugs to treat Helicobacter pylori (H.
pylori) that causes stomach or intestinal ulcers. Metronidazole topical
gel is used for treating acne rosacea, and the vaginal gel is used for
treating bacterial vaginosis.
Dosing: Metronidazole may be taken orally with or without food. In the
hospital, metronidazole can be administered intravenously to treat serious
infections. The liver is primarily responsible for eliminating
metronidazole from the body, and doses may need to be reduced in patients
with liver disease and abnormal liver function.
Where Can I Keep My Medicine?
Keep out of the reach of children in a container that small children
cannot open.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees
F). Protect from light. Throw away any unused medicine after the
expiration date.
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This works. Killed the little ameobas, which were killing me. George.
My symptoms are clearing up well in my mouth and I am very relieved so I
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I would take it again, did a great job on clearing up the infection.
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saved my life-I had a ruptured appendix for 2 days with perionitis and was
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This medicine truly works. I have taken it about 5 times so far. This time
I am on a 14 day dose (2 times a day). I have recurring BV so I have tried
everything more than once. The medicine works on day 2 for me. I am
currently on Day 7. 7 more days to go. I've gotta do it. The taste is soo
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But hey..I would rather go through all that than have this infection.
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